Hwayeon Ryu publishes paper in PLOS Complex Systems

Hwayeon Ryu, associate professor of mathematics, published a paper in PLOS Complex Systems on mathematical modeling framework to guide regimen strategy for phage therapy.

Associate Professor of Mathematics Hwayeon Ryu has published a peer-reviewed paper entitled “Leveraging mathematical modeling framework to guide regimen strategy for phage therapy” in PLOS Complex Systems, a highly regarded journal in the field of computational biology.

This work was from a collaboration with three other mathematical biologists and biologist Dwayne R. Roach who works on phage immunology and pathogenesis at San Diego State University, funded by American Institute of Mathematics through its three-year Structured Quartet Research Ensembles program. In this collaboration, Ryu and co-authors develop and analyze a mathematical model to guide regimen strategy for phage therapy. The findings could lead to a reduction in the risk of complications and failure of phage candidates and speed up the development of more effective phage therapies against antimicrobial resistance disease.

PLOS Complex Systems is part of the highly respected and influential PLOS journals in computational biology. The journal focuses on research to understand the drivers and behaviors of complex systems. Published research cover networks and network theory, nonlinear relationships and the use of data and computational analysis to model and understand complex systems.